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Interaction between CBD & Beta-Blockers

CBD can be quite an efficient disease-buster for people suffering from high blood pressure and heart diseases – the intended effect of beta-blockers. Some people may even opt to use CBD oil instead of beta-blockers as it has the same effect while being a cheaper option with fewer side effects. 

CBD is generally a safe option over other agents and doesn’t usually interact with other medications. However, you must understand that when two chemical agents use the same pathway to enter the bloodstream, there is a possibility of an interaction. 

Both these two chemical compounds require cytochrome P450 – a type of protein, secreted by the liver to metabolize certain kinds of drugs and all toxins introduced into the body. Just like grapefruit, CBD inhibits the breakdown of certain drugs so that it can itself be metabolized, thus hindering the intended effects of the pharmaceutical drugs, like beta-blockers. 

This means it would take the beta-blockers longer time to process, leading to high amounts of its active ingredients remaining in your body in an unprocessed state for a longer period than was intended or is considered safe. 

By now, you must have figured out that if any pharmaceutical drug remains in your body without it being completely metabolized, it can prolong its effects, resulting in certain effects that couldn’t possibly be good for health. 

Adverse effects

Beta-blockers remaining in your body for such a long time could lead to a drastic drop in blood pressure, which can cause:

  • Extreme exhaustion and lethargy
  • Dizziness
  • Weakness
  • Losing consciousness
  • Shock (rare, but would require immediate medical attention)

Safely Using CBD Oil with Beta-Blockers

CBD has proven to combat some side effects caused by beta-blockers, like nausea and fatigue. Taken in small amounts, it curbs dizziness, nausea, and drowsiness caused by these prescription drugs. 

However, the key is to keep the dosage low. While CBD in small doses can induce wakefulness and alertness, and fight nausea and fatigue, it can have quite the opposite effect when taken in high doses, especially if combined with beta-blockers. 

The best thing for someone who is already on beta-blockers and still wants to test CBD on himself is to:

  1. Balance out the dosage of the two chemical compounds to get the desired effect, without causing any damage to the patient’s system.
  2. Consult a naturopath to ascertain if it’s okay to use both together, and how much of each to take.
  3. Test out which kind of delivery method suits the patient’s condition best, keeping the dosage in mind.
  4. Choose brands that offer third-party lab-tested products, sourced from organically grown hemp plants, containing less than 0.3 THC levels. Check their Certificates of Analysis for their genuineness, safety, potency, and quality. 

Taking CBD for overall well being and taking it for some serious illness are two entirely different things. You need to be extremely cautious while combining CBD with medications that interact with CBD (like grapefruit). 

Ivan writes about Cannabis at The Cannabis Radar. He has a degree in Nutrition Sciences from University of Oklahoma Health Sciences Centre. He likes to spend his spare time reading to his daughter or spending time with his wife.

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